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Alpha-1 antitrypsin test

Also called: AAT level, Alpha-1 phenotype

This test checks for alpha-1 antitrypsin deficiency, an inherited cause of COPD and liver disease.

SampleA small tube of blood from a vein in your arm
Fasting?Usually not needed
Results1 to 2 weeks
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

Everyone with COPD should be tested once.

Why it's done

  • COPD, especially at a younger age or without heavy smoking
  • Unexplained liver disease
  • Family history

Getting ready and what happens

  • None.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

Low

Genetic testing confirms the type. Not smoking is critical; some people get replacement infusions.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related tests

Sources

Last updated 2026-11-13.