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Fecal calprotectin

Also called: Stool calprotectin

Fecal calprotectin measures inflammation in the gut. It helps tell inflammatory bowel disease from irritable bowel syndrome.

SampleA stool sample
Fasting?Usually not needed
ResultsSeveral days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

NSAIDs and infections can also raise it.

Why it's done

  • Ongoing diarrhea or belly pain
  • Following Crohn's disease or ulcerative colitis

Getting ready and what happens

  • Avoid NSAIDs for a few days before, if possible.

How the test is done

  • You collect a small stool sample.

What the results mean

ResultTypical range for adults
NormalBelow about 50 mcg/g

Normal ranges vary from lab to lab and can differ by age, sex, and pregnancy. Your report lists your lab's own range next to each result. A result a little outside the range is often not a problem.

High

Suggests gut inflammation; a colonoscopy may follow.

Normal

Makes IBD unlikely and points toward IBS.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Related conditions

Related medicines

Related tests

Sources

Last updated 2026-11-13.