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Lyme disease test

Also called: Lyme antibody test, Lyme Western blot

Lyme disease blood tests look for antibodies to the bacteria spread by blacklegged ticks.

SampleA small tube of blood from a vein in your arm
Fasting?Usually not needed
ResultsSeveral days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

Antibodies take several weeks to show up. A typical bullseye rash after a tick bite is treated without testing.

Why it's done

  • Symptoms like joint swelling, facial drooping, or heart rhythm problems after possible tick exposure

Getting ready and what happens

  • No preparation is needed.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

Positive

With matching symptoms, supports Lyme disease. Antibodies can stay positive after treatment.

Negative early on

May be retested in a few weeks.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related medicines

Sources

Last updated 2026-11-13.