Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.
What the test is
Two types of tests are used together. One type stays positive for life after infection, even after cure.
Why it's done
- Sores on the genitals, mouth, or anus, or a rash on the palms or soles
- Routine STI screening and pregnancy
- A partner with syphilis
Getting ready and what happens
- No preparation is needed.
How the test is done
- A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.
What the results mean
Both tests positive
Means current or past syphilis. Your provider will decide on treatment, usually penicillin.
Following treatment
RPR levels are rechecked to make sure they fall.
When a result needs quick action
Call your provider todayVision or hearing changes, severe headache, or confusion with syphilis
Questions to ask your provider
- What do my results mean for me?
- Do I need to repeat this test or have other tests?
Risks
A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.
Related conditions
Related medicines
Related tests
Sources
Last updated 2026-11-13.