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Vitamin B12 test

Also called: Cobalamin test, B12 level

A vitamin B12 test measures B12 in your blood. Low B12 can cause anemia, tiredness, numbness, and memory problems.

SampleA small tube of blood from a vein in your arm
Fasting?Sometimes 6 to 8 hours
ResultsUsually within 1 to 2 days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

Borderline results may be checked with a methylmalonic acid (MMA) test.

Why it's done

  • Anemia with large red blood cells
  • Numbness, tingling, balance problems, or memory changes
  • Long-term metformin or acid-reducer use
  • Vegan diet, weight-loss surgery, or gut conditions like celiac or Crohn's

Getting ready and what happens

  • Your provider may ask you to fast for 6 to 8 hours.
  • Tell your provider about B12 supplements or shots.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

ResultTypical range for adults
Vitamin B12About 200 to 900 pg/mL

Normal ranges vary from lab to lab and can differ by age, sex, and pregnancy. Your report lists your lab's own range next to each result. A result a little outside the range is often not a problem.

Low (under about 200 pg/mL)

Suggests B12 deficiency. Causes include pernicious anemia, diet, gut absorption problems, and some medicines.

Borderline (about 200 to 300 pg/mL)

May still be low for your body. An MMA or homocysteine test can help decide.

High

Usually from supplements. Rarely linked with liver disease or some blood disorders.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?
  • Do I need B12 shots or will pills work?
  • What's causing my low B12?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related medicines

Related tests

Sources

Last updated 2026-11-13.