ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.
Overview
It doesn't need regular blood tests.
What it's used for
- Psoriasis
- Psoriatic arthritis
- Behçet's mouth ulcers
How to take it
- Follow the 5-day starter pack, then take twice a day.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Diarrhea
- Nausea
- Headache
- Weight loss
Call 911Thoughts of suicide or harming yourself. Call or text 988 any time.
Call your provider todaySevere diarrhea or vomiting
Warnings
- Your provider may watch your weight.
Other medicines, foods, and alcohol
- Rifampin and some seizure medicines lower its effect.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Apremilast (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.