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Contraceptive patch

Brand names: Xulane, Twirla, Zafemy

The birth control patch is worn on the skin and replaced weekly. It releases estrogen and progestin to prevent pregnancy.

Brand namesXulane, Twirla, Zafemy
Type of medicineHormonal birth control
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It may expose you to more estrogen than many pills.

What it's used for

  • Preventing pregnancy

How to take it

  • Apply a new patch the same day each week for 3 weeks, then go patch-free for 1 week.
  • Use clean, dry skin on the buttocks, belly, back, or upper arm (not breasts).

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Skin irritation
  • Breast tenderness
  • Headache
  • Nausea
Call 911Chest pain, sudden shortness of breath, or signs of a stroke
Call your provider todayPain or swelling in one leg

Warnings

  • Boxed warning: higher clot risk; not for women over 35 who smoke.
  • Less effective at higher body weights (some products).

Other medicines, foods, and alcohol

  • Rifampin, some seizure medicines, and St. John's wort make it less effective.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Stop if pregnant.

Missed doses, overdose, and storage

If you miss a dose

If a patch falls off or you're late changing it, follow your insert and use backup birth control as directed.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.