ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.
Overview
It doesn't broadly weaken the immune system like some biologics.
What it's used for
- Moderate to severe eczema
- Moderate to severe asthma
- Nasal polyps with sinus disease
- Eosinophilic esophagitis
- Prurigo nodularis
- Some COPD
How to take it
- Inject under the skin every 2 or 4 weeks after a starting dose.
- Let it warm to room temperature first.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Injection site reactions
- Pink eye or eye irritation
- Cold sores
Call 911Swelling of the face, lips, or throat, hives, or trouble breathing
Call your provider todayEye pain, vision changes, or eyes that stay red
Call your provider todayRash, numbness, or chest symptoms with fever (rare blood vessel inflammation)
Call your provider todayNew joint pain
Warnings
- Don't stop asthma medicines suddenly when starting it.
- Avoid live vaccines.
Other medicines, foods, and alcohol
- Few interactions.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Inject within 7 days of the missed dose, then resume your schedule. Ask if later.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Keep in the refrigerator. It can be kept at room temperature for up to 14 days.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Dupilumab (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.