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Etonogestrel implant

Brand names: Nexplanon

Nexplanon is a matchstick-sized rod placed under the skin of the upper arm. It prevents pregnancy for up to 3 years (often longer).

Brand namesNexplanon
Type of medicineBirth control implant
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's more than 99% effective and can be removed anytime.

What it's used for

  • Preventing pregnancy

How to take it

  • Placed and removed by a trained clinician with numbing medicine.
  • You should be able to feel it under the skin.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Irregular or unpredictable bleeding
  • Headache
  • Weight gain
  • Acne
Call 911Chest pain or signs of a stroke
Call your provider todayCan't feel the implant
Call your provider todaySevere lower belly pain

Warnings

  • It doesn't protect against STIs.

Other medicines, foods, and alcohol

  • Some seizure medicines, rifampin, St. John's wort, and HIV medicines make it less effective.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Remove if pregnant.

Missed doses, overdose, and storage

If you miss a dose

Not applicable: it works continuously. Mark the replacement date.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.