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Felodipine

Brand names: Plendil (brand discontinued)

Felodipine is a once-daily calcium channel blocker that lowers blood pressure.

Brand namesPlendil (brand discontinued)
Type of medicineCalcium channel blocker
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It relaxes blood vessels.

What it's used for

  • High blood pressure

How to take it

  • Swallow extended-release tablets whole, without food or with a light meal.
  • Avoid grapefruit.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Swollen ankles
  • Headache
  • Flushing
Call 911Chest pain or fainting

Warnings

  • Swollen gums can occur; keep up with dental care.

Other medicines, foods, and alcohol

  • Grapefruit juice raises its level a lot.
  • Some antifungals and antibiotics raise it; seizure medicines lower it.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.