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Nifedipine

Brand names: Procardia XL, Adalat CC

Nifedipine relaxes blood vessels to lower blood pressure and prevent angina. It's also used for Raynaud's.

Brand namesProcardia XL, Adalat CC
Type of medicineCalcium channel blocker
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

Extended-release forms are used for long-term treatment.

What it's used for

  • High blood pressure
  • Chest pain (angina)
  • Off-label: Raynaud's phenomenon, high blood pressure in pregnancy

How to take it

  • Swallow extended-release tablets whole. You may see the empty tablet shell in your stool.
  • Take it the same way each day.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Swollen ankles
  • Headache
  • Flushing
  • Dizziness
Call 911Chest pain that's new or worse, or fainting
Call your provider todayFast weight gain or shortness of breath

Warnings

  • Short-acting capsules aren't used for regular blood pressure control.

Other medicines, foods, and alcohol

  • Grapefruit juice raises its level; avoid it.
  • Rifampin and some seizure medicines lower its level; some antifungals raise it.
  • Beta blockers and other blood pressure medicines add to dizziness.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Used for high blood pressure in pregnancy in some cases. Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.