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Galcanezumab

Brand names: Emgality

Galcanezumab (Emgality) is a monthly shot that prevents migraines. It also treats episodic cluster headaches.

Brand namesEmgality
Type of medicineCGRP antibody (migraine prevention)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It blocks CGRP, a protein involved in migraine attacks.

What it's used for

  • Preventing migraines
  • Episodic cluster headaches

How to take it

  • Inject under the skin once a month after a loading dose.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Injection site reactions
Call 911Swelling of the face, lips, or throat, hives, or trouble breathing
Call your provider todayNew or worse high blood pressure

Warnings

  • Allergic reactions can happen days after a dose.

Other medicines, foods, and alcohol

  • Few interactions.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Inject as soon as you remember, then monthly from that date.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Keep in the refrigerator; can stay at room temperature for up to 7 days.

Conditions it's used for

Sources

Last updated 2026-11-13.