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Imiquimod

Brand names: Aldara, Zyclara

Imiquimod cream boosts the skin's immune response to treat genital warts, actinic keratoses, and some superficial skin cancers.

Brand namesAldara, Zyclara
Type of medicineImmune response cream
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

Redness and crusting mean it's working.

What it's used for

  • Genital warts
  • Actinic keratosis (sun damage spots)
  • Superficial basal cell carcinoma

How to take it

  • Apply at bedtime on scheduled days and wash off after 6 to 10 hours.
  • Avoid sex while it's on the skin; it can weaken condoms.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Redness, crusting, and soreness where applied
  • Flu-like symptoms
Call your provider todaySevere skin reaction, open sores, or flu-like illness

Warnings

  • Avoid sun on treated skin.

Other medicines, foods, and alcohol

  • None known.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Ask your provider.

Missed doses, overdose, and storage

If you miss a dose

Apply it when you remember, then go back to your usual schedule. Don't apply extra to make up for it.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.