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Linezolid

Brand names: Zyvox

Linezolid treats serious infections, including MRSA and VRE, as pills or IV.

Brand namesZyvox
Type of medicineOxazolidinone antibiotic
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

Blood counts are checked if used more than 2 weeks.

What it's used for

  • MRSA skin infections
  • Pneumonia
  • VRE infections

How to take it

  • Take it for the full course, even if you feel better.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Diarrhea
  • Headache
  • Nausea
Call 911Agitation, fever, sweating, muscle twitching or stiffness, fast heartbeat, and confusion (possible serotonin syndrome)
Call your provider todayUnusual bruising or bleeding
Call your provider todayVision changes or numbness (with long use)
Call your provider todaySevere watery or bloody diarrhea, even weeks after finishing (possible C. diff infection)

Warnings

  • Avoid large amounts of high-tyramine foods (aged cheese, cured meats, tap beer, soy sauce).

Other medicines, foods, and alcohol

  • SSRIs, SNRIs, and other serotonin medicines can cause serotonin syndrome.
  • Decongestants can raise blood pressure.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember. If it's almost time for the next dose, skip the missed one. Don't double up, and still finish the full course.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.