Overview
It treats the symptom, not the cause. Drink fluids to replace what you lose.
What it's used for
- Short-term diarrhea
- Traveler's diarrhea
- Long-lasting diarrhea from some conditions (with a provider's advice)
How to take it
- Follow the label. Never take more than the label allows; very high doses can cause deadly heart rhythm problems.
- Stop and see a provider if diarrhea lasts more than 2 days.
- Don't give it to children under 6 unless a provider says to.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Constipation
- Belly cramps
- Dizziness
Warnings
- Don't use it with bloody diarrhea or high fever unless a provider says to; it can trap germs.
- Don't use it for diarrhea after antibiotics without asking (possible C. diff).
Other medicines, foods, and alcohol
- Some medicines (like itraconazole, ritonavir, and quinidine) raise its level and heart risks.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Ask your provider before using it in pregnancy.
Missed doses, overdose, and storage
If you miss a dose
This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Loperamide (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.