ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.
Overview
It's raised slowly over a week.
What it's used for
- Fibromyalgia
How to take it
- Take it twice a day with food.
- Don't stop suddenly.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Nausea
- Headache
- Sweating
- Fast heartbeat
- Hot flashes
Call 911Thoughts of suicide or harming yourself. Call or text 988 any time.
Call 911Agitation, fever, sweating, muscle twitching or stiffness, fast heartbeat, and confusion (possible serotonin syndrome)
Call your provider todayHigh blood pressure readings
Warnings
- Children, teens, and young adults can have more suicidal thoughts when starting. Watch closely in the first weeks.
Other medicines, foods, and alcohol
- Never take within 14 days of an MAOI.
- Other serotonin medicines add risk.
- Aspirin, NSAIDs, and blood thinners raise bleeding risk.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Milnacipran (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.