Health information to help you understand symptoms. It isn't a diagnosis.
Check symptoms

Pseudoephedrine

Brand names: Sudafed, Claritin-D (in combination)

Pseudoephedrine is a decongestant that shrinks swollen nasal passages to relieve stuffiness.

Brand namesSudafed, Claritin-D (in combination)
Type of medicineDecongestant
Prescription?Over the counter (kept behind the pharmacy counter)
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's kept behind the pharmacy counter and you need ID to buy it. Phenylephrine, the version on the shelf, works much less well.

What it's used for

  • Stuffy nose from colds, allergies, and sinus congestion

How to take it

  • Follow the label. Take it earlier in the day to avoid trouble sleeping.
  • Don't use it longer than 7 days without asking a provider.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Trouble sleeping
  • Nervousness
  • Fast heartbeat
  • Dizziness
Call 911Chest pain, a racing or irregular heartbeat, or a severe headache
Call your provider todayTrouble peeing

Warnings

  • Ask a provider first if you have high blood pressure, heart disease, glaucoma, an enlarged prostate, diabetes, or thyroid disease.
  • Don't give to children under 4.

Other medicines, foods, and alcohol

  • Never take within 14 days of an MAOI.
  • Stimulants and caffeine add to its effects.
  • It can weaken blood pressure medicines.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Avoid in the first trimester. Ask your provider.

Missed doses, overdose, and storage

If you miss a dose

This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.