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Rimegepant

Brand names: Nurtec ODT

Rimegepant (Nurtec) is a dissolving tablet that both treats migraine attacks and, taken every other day, helps prevent them.

Brand namesNurtec ODT
Type of medicineGepant (migraine medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It blocks the CGRP receptor. It doesn't narrow blood vessels.

What it's used for

  • Treating migraine attacks
  • Preventing episodic migraines

How to take it

  • Place it on or under the tongue; it dissolves without water.
  • Don't take more than one in 24 hours.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Nausea
  • Stomach pain
Call 911Swelling of the face, lips, or throat, hives, or trouble breathing
Call your provider todayNew or worse high blood pressure

Warnings

  • Avoid with strong CYP3A4 drugs.

Other medicines, foods, and alcohol

  • Some antifungals and antibiotics raise its level; rifampin lowers it.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.