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Ubrogepant

Brand names: Ubrelvy

Ubrogepant (Ubrelvy) stops a migraine attack. It's an option for people who can't take triptans.

Brand namesUbrelvy
Type of medicineGepant (migraine medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It blocks CGRP, a protein involved in migraine pain. It doesn't narrow blood vessels like triptans do.

What it's used for

  • Treating migraine attacks

How to take it

  • Take it at the onset of a migraine; a second dose may be allowed after 2 hours.
  • Follow the daily limit on your label.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Nausea
  • Sleepiness
  • Dry mouth
Call 911Swelling of the face, lips, or throat, hives, or trouble breathing
Call your provider todayNew or worse high blood pressure or Raynaud's symptoms

Warnings

  • Don't use with strong CYP3A4 blockers like ketoconazole or clarithromycin.

Other medicines, foods, and alcohol

  • Some antifungals, antibiotics, and grapefruit juice raise its level.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.