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Silodosin

Brand names: Rapaflo

Silodosin relaxes the prostate to ease urinary symptoms of an enlarged prostate.

Brand namesRapaflo
Type of medicineAlpha blocker (prostate medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's also used off-label to help pass kidney stones.

What it's used for

  • Enlarged prostate (BPH)
  • Off-label: helping pass kidney stones

How to take it

  • Take it once a day with a meal.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Little or no semen with orgasm
  • Dizziness
  • Stuffy nose
Call 911Fainting
Call 911An erection lasting more than 4 hours

Warnings

  • Tell your eye surgeon you take it before cataract surgery.
  • Stand up slowly.
  • Not for people with severe kidney or liver disease.

Other medicines, foods, and alcohol

  • Strong CYP3A4 blockers must not be combined.
  • Other alpha blockers add to dizziness.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Not used in women.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.