If you think it's an emergency, call 911.Thinking about suicide or in crisis? Call or text 988.Being hurt or threatened at home? National Domestic Violence Hotline: 1-800-799-7233.Help with alcohol or drug use: SAMHSA Helpline, 1-800-662-4357.
Overview
Depression affects how you think about yourself.
Treatment works.
When to get medical care
Call 911Thoughts of harming yourself or others: call or text 988, or call 911 if you're in danger.
Get care todayFeeling unable to cope.
See a doctor soonLow mood or guilt lasting weeks.
Causes
Causes include depression and stress.
OwieClear has pages on 1 condition that can cause feeling worthless or guilty. Each shows how soon to get care.
Common causes
- DepressionSee a doctor if it doesn't get better
A persistent low mood or loss of interest that lasts at least 2 weeks.
What you can do at home
- Talk to someone you trust.
Medicines
Therapy and antidepressants.
At the doctor
The provider will ask about mood.
Questions you may be asked
- Mood
- Safety
The exam
A physical exam.
Tests
- Depression screening
Prevention
Get help.
- Stay connected
Check your symptoms
Most symptoms have more than one possible cause. The symptom checker looks at all of your symptoms together, plus your age, and shows how soon to get care.
Sources
Last updated 2026-11-13.