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Celiac disease test

Also called: tTG-IgA, Tissue transglutaminase antibody, Celiac panel

Celiac blood tests look for antibodies triggered by gluten. They're the first step in diagnosing celiac disease.

SampleA small tube of blood from a vein in your arm
Fasting?Usually not needed
ResultsSeveral days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

You must be eating gluten for the test to be accurate. A positive result is usually confirmed with an endoscopy and biopsy.

Why it's done

  • Diarrhea, bloating, weight loss, or iron deficiency
  • A family member with celiac disease
  • Type 1 diabetes or thyroid disease

Getting ready and what happens

  • Keep eating gluten (about 2 slices of bread a day) for several weeks before testing.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

Positive

Celiac is likely; an endoscopy confirms it. Don't stop gluten until testing is complete.

Negative

Celiac is unlikely if you were eating gluten.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related tests

Sources

Last updated 2026-11-13.