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Creatinine and eGFR

Also called: eGFR, Kidney function test, Serum creatinine, GFR

Creatinine is a waste product cleared by the kidneys. Your eGFR, calculated from creatinine, estimates how well your kidneys filter blood.

SampleA small tube of blood from a vein in your arm
Fasting?Usually not needed
ResultsOften the same day
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

eGFR is reported as part of most basic and comprehensive metabolic panels.

Muscle mass, dehydration, and some supplements (like creatine) can affect creatinine. A cystatin C test can help confirm.

Why it's done

  • Checking kidney function in diabetes, high blood pressure, or heart disease
  • Before and during medicines that affect the kidneys
  • Swelling, changes in peeing, or other kidney symptoms

Getting ready and what happens

  • Avoid heavy exercise and large amounts of meat the day before, if your provider asks.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

ResultTypical range for adults
eGFR90 or higher is normal; 60 to 89 is mildly reduced (may be normal with age)
Chronic kidney diseaseeGFR below 60 for 3 months or more
Kidney failureeGFR below 15

Normal ranges vary from lab to lab and can differ by age, sex, and pregnancy. Your report lists your lab's own range next to each result. A result a little outside the range is often not a problem.

Low eGFR

May mean kidney disease, dehydration, or a medicine effect. A single low result is usually repeated. A urine albumin test helps stage kidney disease.

Sudden rise in creatinine

Can be acute kidney injury from dehydration, infection, blockage, or medicines and needs prompt attention.

When a result needs quick action

Call your provider todayA sudden big rise in creatinine, especially with much less urine, swelling, or vomiting

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?
  • Do I have kidney disease, and what stage?
  • Do any of my medicines need a dose change?
  • Should I avoid NSAIDs like ibuprofen?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related medicines

Related tests

Sources

Last updated 2026-11-13.