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Spinal fluid analysis

Also called: CSF analysis, Lumbar puncture, Spinal tap

Spinal fluid tests check the fluid around the brain and spinal cord for infection, bleeding, and inflammation.

SampleSpinal fluid
Fasting?Usually not needed
ResultsHours to days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

Fluid is collected with a lumbar puncture (spinal tap) in the lower back.

Why it's done

  • Possible meningitis or encephalitis
  • Possible bleeding around the brain with a normal CT
  • Multiple sclerosis and other nerve conditions

Getting ready and what happens

  • Tell your provider about blood thinners.

How the test is done

  • You lie on your side or sit bent forward. After numbing, a thin needle is placed between the lower back bones to collect fluid.

What the results mean

Signs of infection

High white cells and protein with low sugar suggest bacterial meningitis, which is treated urgently.

When a result needs quick action

Call 911Fever with stiff neck, confusion, or a purple rash that doesn't fade

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

Some people get a headache afterward, which improves lying flat. Bleeding and infection are rare.

Related conditions

Related tests

Sources

Last updated 2026-11-13.