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Cystatin C

Also called: Cystatin C eGFR

Cystatin C is another marker of kidney function. It's less affected by muscle mass than creatinine.

SampleA small tube of blood from a vein in your arm
Fasting?Usually not needed
ResultsUsually within 1 to 2 days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

Combined creatinine-cystatin C eGFR is often the most accurate estimate.

Why it's done

  • Confirming a borderline eGFR
  • Very high or low muscle mass
  • Medicine dosing decisions

Getting ready and what happens

  • No special preparation is needed.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

High

Suggests reduced kidney function. Thyroid problems and high-dose steroids can also affect it.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related tests

Sources

Last updated 2026-11-13.