Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.
What the test is
Anti-CCP is more specific for rheumatoid arthritis. RF can be positive in healthy older adults and with other conditions.
Why it's done
- Joint pain, swelling, and morning stiffness, especially in the hands and feet
Getting ready and what happens
- No special preparation is needed.
How the test is done
- A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.
What the results mean
| Result | Typical range for adults |
|---|---|
| RF | Below about 14 IU/mL (labs vary) |
| Anti-CCP | Below about 20 units (labs vary) |
Normal ranges vary from lab to lab and can differ by age, sex, and pregnancy. Your report lists your lab's own range next to each result. A result a little outside the range is often not a problem.
Positive
With matching symptoms, supports rheumatoid arthritis. A positive anti-CCP also suggests a higher chance of joint damage.
Negative
Doesn't rule out rheumatoid arthritis; some people never test positive.
Questions to ask your provider
- What do my results mean for me?
- Do I need to repeat this test or have other tests?
- Should I see a rheumatologist?
- Do I need X-rays?
Risks
A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.
Related conditions
Related medicines
Related tests
Sources
Last updated 2026-11-13.