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Total protein test

Also called: Serum protein, Albumin/globulin ratio

Total protein measures albumin and globulins in your blood. It's part of the comprehensive metabolic panel.

SampleA small tube of blood from a vein in your arm
Fasting?Usually not needed
ResultsOften the same day
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

It's part of the comprehensive metabolic panel (CMP).

Why it's done

  • Routine panels
  • Swelling, weight loss, or liver or kidney disease

Getting ready and what happens

  • No special preparation is needed.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

ResultTypical range for adults
Total proteinAbout 6.0 to 8.3 g/dL

Normal ranges vary from lab to lab and can differ by age, sex, and pregnancy. Your report lists your lab's own range next to each result. A result a little outside the range is often not a problem.

High

Can come from dehydration, long-term inflammation, or, with a high globulin gap, conditions like multiple myeloma.

Low

Can come from liver disease, kidney protein loss, or malnutrition.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related tests

Sources

Last updated 2026-11-13.