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Vitamin B6 test

Also called: Pyridoxal 5'-phosphate, PLP

A vitamin B6 test checks for low or high B6. Both can cause nerve problems.

SampleA small tube of blood from a vein in your arm
Fasting?Sometimes
ResultsSeveral days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

Too much B6 from supplements can cause numbness.

Why it's done

  • Numbness or tingling
  • Some medicines, alcohol use, or kidney disease
  • Taking high-dose supplements

Getting ready and what happens

  • Fast overnight if asked; stop B6 supplements beforehand only if told to.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

Low

Supplements and diet changes help.

High

Usually from supplements; stopping them often improves symptoms.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related tests

Sources

Last updated 2026-11-13.