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Clotrimazole

Brand names: Lotrimin AF, Gyne-Lotrimin, Mycelex troche

Clotrimazole is an antifungal for athlete's foot, jock itch, ringworm, and vaginal yeast infections. Lozenges treat thrush.

Brand namesLotrimin AF, Gyne-Lotrimin, Mycelex troche
Type of medicineAntifungal
Prescription?Over the counter (creams); prescription (lozenges)
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

Keep using it for the full time on the label, even after the rash looks better.

What it's used for

  • Athlete's foot, jock itch, and ringworm
  • Vaginal yeast infections
  • Oral thrush (lozenges)

How to take it

  • Skin: apply to clean, dry skin and a little beyond, usually twice a day, for 2 to 4 weeks.
  • Vaginal: use at bedtime for the number of days on the package.
  • Lozenges: let them dissolve slowly in the mouth.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Burning, stinging, or itching
Call 911Swelling of the face, lips, or throat, hives, or trouble breathing
Call your provider todayFever, belly pain, or foul-smelling discharge with vaginal symptoms

Warnings

  • See a provider for a first yeast infection, frequent ones, or if not better in 3 to 7 days.
  • Vaginal products can weaken condoms and diaphragms.

Other medicines, foods, and alcohol

  • Lozenges can raise tacrolimus levels.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Vaginal clotrimazole is commonly used in pregnancy. Ask your provider.

Missed doses, overdose, and storage

If you miss a dose

Apply it when you remember, then go back to your usual schedule. Don't apply extra to make up for it.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.