Overview
Delayed-onset muscle soreness (DOMS) happens when muscles work harder than they're used to, causing tiny injuries. It peaks 1 to 3 days after exercise and gets better on its own.
A strain (pulled muscle) causes sudden pain during activity, sometimes with bruising or swelling. Rarely, very intense exercise, heat, or certain medicines can break down muscle tissue (rhabdomyolysis), which can harm the kidneys.
When to get medical care
Causes
Common causes include delayed-onset muscle soreness, overuse, muscle strains, cramps, and dehydration. Other causes include rhabdomyolysis, compartment syndrome, statins and other medicines, low potassium or other electrolyte problems, and an underactive thyroid.
OwieClear has pages on 2 conditions that can cause muscle pain after activity. Each shows how soon to get care.
Common causes
- Muscle aches (myalgia)Often treated at home
Aching, tender, or sore muscles.
- Muscle strain or low back painOften treated at home
Overstretched or tight muscles, often from lifting or activity.
What you can do at home
- Rest the sore muscles, but keep moving gently.
- Use ice for the first day or two after a strain, then heat.
- Stretch gently and try massage.
- Drink plenty of water.
- Build up exercise slowly, increasing by no more than about 10% a week.
- Warm up before and cool down after exercise.
Medicines
Acetaminophen (Tylenol) or ibuprofen (Advil, Motrin) can ease soreness. Don't take ibuprofen if you have dark urine or might be dehydrated. Tell your provider if you think a medicine is causing muscle pain.
At the doctor
The provider will check for a strain or muscle breakdown.
Questions you may be asked
- What activity you did and when the pain started
- Whether pain came on suddenly
- Urine color
- Swelling, weakness, or numbness
- Your medicines
The exam
A physical exam of the muscles and strength.
Tests
- Blood test for muscle damage (CK)
- Urine test
- Kidney function tests
- An ultrasound or MRI for strains
Prevention
You can lower your risk.
- Build up exercise gradually
- Warm up and stretch
- Drink fluids, especially in heat
- Rest between hard workouts
Check your symptoms
Most symptoms have more than one possible cause. The symptom checker looks at all of your symptoms together, plus your age, and shows how soon to get care.
Sources
Last updated 2026-11-13.