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Methylmalonic acid (MMA)

Also called: MMA test

The MMA test helps confirm vitamin B12 deficiency when the B12 level is borderline.

SampleA small tube of blood from a vein in your arm
Fasting?Usually not needed
ResultsSeveral days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

MMA rises when your cells don't have enough B12.

Why it's done

  • Borderline B12 level
  • Numbness, memory problems, or anemia possibly from low B12

Getting ready and what happens

  • No special preparation is usually needed.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

High

Supports B12 deficiency. Kidney disease can also raise it.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

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Sources

Last updated 2026-11-13.