Health information to help you understand symptoms. It isn't a diagnosis.
Check symptoms

Homocysteine test

Also called: Total homocysteine

A homocysteine test measures an amino acid that rises when B12, folate, or B6 is low.

SampleA small tube of blood from a vein in your arm
Fasting?Often 8 to 12 hours
ResultsUsually within 1 to 2 days
Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.

What the test is

High levels are linked with blood clots and heart disease, but lowering it with vitamins hasn't been shown to prevent heart attacks.

Why it's done

  • Borderline B12 or folate results
  • Unexplained clots at a young age

Getting ready and what happens

  • You may be asked to fast for 8 to 12 hours.

How the test is done

  • A health worker cleans the skin, puts a band around your arm, and draws blood from a vein with a small needle. It takes a few minutes.

What the results mean

ResultTypical range for adults
HomocysteineAbout 5 to 15 micromol/L

Normal ranges vary from lab to lab and can differ by age, sex, and pregnancy. Your report lists your lab's own range next to each result. A result a little outside the range is often not a problem.

High

Often from low B12 or folate, kidney disease, or a genetic difference.

Questions to ask your provider

  • What do my results mean for me?
  • Do I need to repeat this test or have other tests?

Risks

A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.

Related conditions

Related medicines

Related tests

Sources

Last updated 2026-11-13.