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Desloratadine

Brand names: Clarinex

Desloratadine is a once-daily, non-drowsy antihistamine for allergies and chronic hives.

Brand namesClarinex
Type of medicineAntihistamine (allergy medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's the active form of loratadine.

What it's used for

  • Seasonal and indoor allergies
  • Chronic hives

How to take it

  • Take it once a day, with or without food.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Headache
  • Dry mouth
  • Sore throat
Call 911Swelling of the face, lips, or throat, hives, or trouble breathing

Warnings

  • Doses may be lower with liver or kidney disease.

Other medicines, foods, and alcohol

  • Few interactions.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Ask your provider.

Missed doses, overdose, and storage

If you miss a dose

This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.