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Fexofenadine

Brand names: Allegra

Fexofenadine is a non-drowsy antihistamine that relieves allergy symptoms and hives.

Brand namesAllegra
Type of medicineAntihistamine (allergy medicine)
Prescription?Over the counter
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's one of the least sedating allergy pills.

What it's used for

  • Seasonal and indoor allergies
  • Hives

How to take it

  • Take it with water, not fruit juice. Juice (apple, orange, grapefruit) lowers how much is absorbed.
  • Follow the label for age and dose.
  • Separate it from antacids by about 2 hours.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Headache
  • Upset stomach
Call 911Swelling of the face, lips, or throat, hives, or trouble breathing

Warnings

  • Ask a provider first if you have kidney disease.

Other medicines, foods, and alcohol

  • Fruit juices and antacids lower absorption.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Ask your provider before using it in pregnancy or while breastfeeding.

Missed doses, overdose, and storage

If you miss a dose

This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.